Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, (1S,4aS,5S,7aS)-
Paederosidic acid
CAS: 18842-98-3
Molecular Formula: C18H24O12S
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, (1S,4aS,5S,7aS)- - Names and Identifiers
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, (1S,4aS,5S,7aS)- - Physico-chemical Properties
| Molecular Formula | C18H24O12S |
| Molar Mass | 464.44 |
| Density | 1.67±0.1 g/cm3(Predicted) |
| Boling Point | 748.1±70.0 °C(Predicted) |
| Specific Rotation(α) | (c, 0.13 in MeOH)+19 |
| Solubility | Soluble in methanol |
| Appearance | Yellow powder |
| pKa | 4.30±0.70(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD28124366 |
| Physical and Chemical Properties | Yellow powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from the scandense of chicken excrement vine Paederia. |
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, (1S,4aS,5S,7aS)- - Reference
| Reference Show more | 1. Shi Guirong, Ren Bowen, du Xuzhao, etc. Effect of paeonol on inflammatory response of articular chondrocytes induced by IL-1β [J]. Chinese traditional medicines, 2020, v.42(06):230-533. 2. Yu, Ping, et al. "Antitumor activity of paderosidic acid in human non-small cell lung cancer cells via induction mitochondria-mediated apotosis." Chemico-biological interactions 269 (2017): 33-43. https:// doi.org/10.1016/j. 2/003 2017 3. [IF = 3.723] Ping Yu et al."Antitumor activity of paederosidic acid in human non-small cell lung cancer cells via inducing mitochondria-mediated apoptosis."Chem-Biol Interact. 2017 May;269:33 4. [IF=2.419] Zhiyong Zhang et al."An integration of UPLC-Q-TOF/MS and chemometrics analysis for the holistic quality evaluation of different geographical Paederia scandens."RAPID COMMUNICATIONS IN MASS SPECTROMETRY. 2022 Jul;36(13):e9317 |
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, (1S,4aS,5S,7aS)- - Introduction
Paederosidic acid, also known as oxymatrine, is a natural product, which has a wide range of applications in Chinese herbal medicine. The following is a detailed introduction to Paederosidic acid:
Nature:
Paederosidic acid is a white crystalline solid with the chemical formula C30H48O3. It is a triterpenoid natural product with a bitter taste and slightly soluble in water.
Use:
1. Anti-inflammatory and antioxidant: Paederosidic acid has anti-inflammatory and antioxidant effects and is widely used in traditional Chinese medicine and health care products to treat inflammation-related diseases and provide antioxidant protection.
2. Anti-tumor: Paederosidic acid also has potential anti-tumor activity, so it has also received certain attention in the field of tumor treatment.
Preparation Method:
Paederosidic acid can be extracted from Chinese herbal medicine such as Sophora. The extraction process mainly includes the crushing of Sophora flavesense herbs, the solvent extraction of the extract, the volatilization of the solvent and the crystallization of the solvent.
Safety Information:
The use of Paederosidic acid is generally considered to be relatively safe, but long-term or high-dose use may produce certain adverse reactions and toxicity. Consult a doctor or professional before use and follow the correct usage and dosage. At the same time, for specific groups such as pregnant women, lactating women and children, a doctor should be consulted before use.
Nature:
Paederosidic acid is a white crystalline solid with the chemical formula C30H48O3. It is a triterpenoid natural product with a bitter taste and slightly soluble in water.
Use:
1. Anti-inflammatory and antioxidant: Paederosidic acid has anti-inflammatory and antioxidant effects and is widely used in traditional Chinese medicine and health care products to treat inflammation-related diseases and provide antioxidant protection.
2. Anti-tumor: Paederosidic acid also has potential anti-tumor activity, so it has also received certain attention in the field of tumor treatment.
Preparation Method:
Paederosidic acid can be extracted from Chinese herbal medicine such as Sophora. The extraction process mainly includes the crushing of Sophora flavesense herbs, the solvent extraction of the extract, the volatilization of the solvent and the crystallization of the solvent.
Safety Information:
The use of Paederosidic acid is generally considered to be relatively safe, but long-term or high-dose use may produce certain adverse reactions and toxicity. Consult a doctor or professional before use and follow the correct usage and dosage. At the same time, for specific groups such as pregnant women, lactating women and children, a doctor should be consulted before use.
Last Update：2024-04-10 22:29:15
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Product Name: Paederosidic acid Visit Supplier Webpage Request for quotationCAS: 18842-98-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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